By Shayne C. Gad
Even though i've got but to learn the ebook in its entirety, i've got skimmed via a number of chapters & i locate that a lot of the innovations seem to be written in redundancy. maybe i've got excessive expectancies, yet might be concepts which are played within the comparable demeanour among species may be consolidated and referenced. the data for real toxicology within the a number of species is especially helpful.
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Additional resources for Animal Models in Toxicology
Ziegler, D. M. (1988). Flavin-containing monooxygenase: Catalytic mechanism and specificities. Drug Metab. Rev. 19, 1–32. fm Page 19 Thursday, August 31, 2006 10:30 PM CHAPTER 2 The Mouse Toxicology: Shayne C. Gad Gad Consulting Services Pathology: Charles H. Frith Toxicology Pathology Associates Dawn G. Goodman PATHCO, Inc. Byron G. Boysen Hazleton Wisconsin, Inc. Metabolism: Shayne C. 130 TOXICOLOGY History The domesticated mouse of North America and Europe (Mus musculus) is the most widely used animal in medical research.
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Toxicol. 18, 81–96. Levy, R. , Thummel, K. , Tragen, W. , Hanslen, P. , and Eichelbaum, M. (2000). Metabolic drug interactions. Philadelphia: Lippincott, Williams & Wilkins. Lewis, D. F. V. (2001). Guide to cytochrome P450. Philadelphia: Taylor & Francis. , and Bryan, G. (1973). Enzymatic N-acetylation of carcinogenic aromatic amines by liver cytosol of species displaying different oran susceptibilities. Biochem. Pharmacol. 22, 1581–1588. , and Gram, T. (1975). Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species.
Animal Models in Toxicology by Shayne C. Gad